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GLUCOSE (GLUCOSUM)
INSTRUCTION TO PREPARATION

PHARMACOLOGICAL PROPERTY: 5% solution of glucose is isotonic towards blood plasma and when injecting it intravenously refills the volume of circulating blood after its loss, provides substrate enrichment of energy expenditure.

INDICATION TO ADMINISTRATION: Enrichment of volume of circulating blood (at anhydration as consequence of emesis, diarrhea, while after-surgery period, while shock, collapse); blocking of lungs, hypogliycemic conditions, characteristic for diabetes-ill persons during sugar-reducing therapy, as a dissolving agent or infusion environment for injection of other medicaments. Preparation is also used for refilling insufficiency of carbohydrates in organism while physical and mental strain.

ROUT:  Isotonic solution is injected subdermaly, intravenously dropwise and in clysters. Adults and children after 15 receive subdermaly and intravenous dropwise injection of 300-500 ml and more per 24 hours in nutrient environment in clysters from 300-500 ml to 1000-2000 ml per 24 hours, preferably dropwise. Maximum doze of liquid for routine clinical usage must not exeed 2 l/24 hours, incase of shock condition - maximum 2 l/hour. Maximum doze of Glucose in 24 hours constitutes 0,75 gr/kg of body weight per hour.
For children in case of necessity of enrichment of circulating blood volume dosage of 5% of Glucose solution is conducted taking into account the defissiency of liquid in organism and child's need of liquid, which constitutes: for children under 1year old 130-150 ml/kg/24 hours; for children after 1 year old, as well as for adults, 20-30 ml/kg/24 hours .
 Volume of nurutive clyster with 5% solution of glucose must correspond to the child's age in the same doze, as for intravenous infusions, preferably dropwise.

SIDE EFFECT: Not found.

CONTRAINDICATION: Diabetes and different states accompanied by hyperglycemia.

CORRELATION WITH OTHER PHARMARMACEUTICALS: Preparation contains chloride-carbohydrate acid. Preparation may be used as dissolvent for preparations which are destabilized in acidulous р═.

OVERDOSAGE: Development of hyperglycemia is possible. In this case patients feel dryness of skin, and of mucous coats, decrease of tension of eye-bulb, frequent shallow breast without acetone smell, tachycardia, arrhythmia, faintness, increasing of temperature. In case of overdosage symptomatic treatment and injection of preparations of usual insulin in doze of 0,1 Unit/kg intramuscularly or subdermally should be prescribed.

SPECIFICS OF ADMINISTRATION. During intravenous use of preparation control of level of sugar in blood is necessary.

STORAGE CONDITIONS: keep far from the reach of children at temperature not higher than +25╤. Freezing of preparation preserving hermeticity of a bottle is not a contraindication to administration of the preparation. Impermeability of internal surface of a bottle is not a contraindication to administration of the preparation.